Hi, Tony,
I have not been using GIS for RTR but only to access config server, and here are my experiences so far:
Bad things:
1. limited XML capabilities that are very hard to debug
2. it has a tendency to time out (you have to keep you client pinging GIS every 10 second or so to make sure that you do not lose your session)
3. even on the LAN, reply times are taking seconds, not milliseconds you would usually expect
4. dealing with large amount of data requires multiple submits, significantly destroying the performance
5. no packet compression, meaning if you have 5000 agents you want to get info for, you get a LOT of data sent your way over the wire. If you have 10 clients trying to do it at the same time, things get ugly
Good things:
1. easy to install an operate
2. XML documentation can be better, but you get xml file that pretty much tells you everything
3. allows you to work directly with config server
4. (My favorite) I love .NET and I found that GIS and .NET usually work very well because of XML support built into .NET
Have not dealt with RTR but after seeing the price tag, I am having second thoughts, because most of the stats can be retrieved via URS (poor man's way

)
Hope it helped!
Vic